hsa-miR-27a-3p

ncRNA information

ncRNA name

hsa-miR-27a-3p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

BTG2

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Adriamycin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MicroRNA-27a-3p Reverses Adriamycin Resistance by Targeting BTG2

Tissue resource

human chemosensitive breast cancer cell lines MCF-7

human breast cancer adriamycin-resistant cell lines MCF-7/ADR

Experiment

None


Institute

American Type Culture Collection

Xinyu Biotechnology

Country

United States

China

Continent

North Amercian

Asia