hsa-miR-520h

ncRNA information

ncRNA name

hsa-miR-520h

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

OTUD3/PTEN

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

miR-520h Stimulates Drug Resistance to Paclitaxel by Targeting the OTUD3-PTEN Axis in Breast Cancer

Tissue resource

paired breast cancer tumor tissues and matched adjacent normal tissues

breast cancer cell lines MCF-7

breast cancer paclitaxel-resistant cell lines MCF-7/Taxol

Experiment

None


Institute

Breast Department of Qilu Hospital of Shandong University

American Type Culture Collection

GeneChem

Country

China

United States

China

Continent

Asia

North Amercian

Asia