CircTNPO3

ncRNA information

ncRNA name

CircTNPO3

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-1299/NEK2

Cancer information

Cancer name

Ovarian Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

20(<55)+28(>=55)

Age range and number

Not available

Research information

PMID

Description

Circular RNA circTNPO3 Regulates Paclitaxel Resistance of Ovarian Cancer Cells by miR-1299/NEK2 Signaling Pathway

Tissue resource

paired resected ovarian cancer tissues and adjacent normal tissues

human ovarian carcinoma cell lines SKOV3

human ovarian carcinoma cell lines HeyA-8

normal ovarian epithelial cell lines IOSE-80

Experiment

48


Institute

Affiliated Tumor Hospital of Xiang-Ya School of Medicine

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian