ncRNA name
CircRNA_103809
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-516a-5p/FBXL18
Cancer name
Bladder Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Gemcitabine
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Circular RNA circRNA_103809 Accelerates Bladder Cancer Progression and Enhances Chemo-Resistance by Activation of miR-516a-5p/FBXL18 Axis
Tissue resource
bladder cancer tissues and corresponding adjacent normal tissues
bladder cancer cell lines SV-HUC-1
bladder cancer cell lines EJ
bladder cancer cell lines UMUC3
bladder cancer cell lines T24
human immortalized uroepithelium cell line SV-HUC-1
Experiment
None
Institute
the First Affiliated Hospital of Wenzhou Medical University
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian