KCNQ1OT1

ncRNA information

ncRNA name

KCNQ1OT1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-27b-3p/ATF2

Cancer information

Cancer name

Chondrosarcoma

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Long Non-Coding RNA KCNQ1OT1 Promotes Multidrug Resistance in Chordoma

Tissue resource

serum samples were collected from chordoma patients

chordoma cell lines JHC7

chordoma cell lines U-CH1

Experiment

None


Institute

the Second Xiangya Hospital with Central South University

Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences

Country

China

China

Continent

Asia

Asia