Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
HOTAIR
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-149-5p/DCLK1
Cancer name
Non-Small Cell Lung Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
38
Male patients
32
Female patients
31(<60)+39(>=60)
Age range and number
Not available
PMID
Description
Knockdown of Long Non-Coding RNA HOTAIR Suppresses Cisplatin Resistance
Tissue resource
non-small cell lung cancer tumor tissues
human non-small cell lung cancer cell lines A549
human non-small cell lung cancer cell lines H1299
Experiment
70
Institute
the Affiliated Tumor Hospital of Xinjiang Medical University
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.