LUCAT1

ncRNA information

ncRNA name

LUCAT1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-514a-3p/ULK1

Cancer information

Cancer name

Non-Small Cell Lung Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

32

Male patients

28

Female patients

32(<=65)+28(>65)

Age range and number

Not available

Research information

PMID

Description

Long non-coding RNA LUCAT1 contributes to cisplatin resistance by regulating the miR-514a-3p/ULK1 axis in human non-small cell lung cancer

Tissue resource

cisplatin-resistant non-small cell lung cancer tissues and cisplatin-sensitive non-small cell lung cancer tissues and tumor-adjacent normal tissues

normal human lung fibroblasts cell lines IMR90

non-small cell lung cancer cell lines A549

Experiment

60


Institute

First Hospital of China Medical University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian