CircPSMC3

ncRNA information

ncRNA name

CircPSMC3

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-10a-5p/PTEN

Cancer information

Cancer name

Esophageal Squamous Cell Carcinoma

Cancer site

None

Treatment information

Treatment type

Chemotherapy

Drug

Gefitinib

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

upregulation of circPSMC3 overcame resistance of GR ESCC cells to gefitinib by modulating the miR-10a-5p/PTEN axis

Tissue resource

Experiment

None


Institute

Country

Continent