CASC9

ncRNA information

ncRNA name

CASC9

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

DUSP1

Cancer information

Cancer name

Non-Small Cell Lung Cancer

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Gefitinib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Long non-coding RNA CASC9 promotes gefitinib resistance in NSCLC by epigenetic repression of DUSP1

Tissue resource

non-small cell lung cancer specimen tissues

non-small cell lung cancer cell lines PC9

non-small cell lung cancer cell lines HCC827

non-small cell lung cancer cell lines H1975

Experiment

None


Institute

The Second Affiliated Hospital of Nanjing Medical University

Institute of Biochemistry and Cell Biology at the Chinese Academy of Sciences

Country

China

China

Continent

Asia

Asia