ncRNA name
CASC9
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
DUSP1
Cancer name
Non-Small Cell Lung Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Gefitinib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Long non-coding RNA CASC9 promotes gefitinib resistance in NSCLC by epigenetic repression of DUSP1
Tissue resource
non-small cell lung cancer specimen tissues
non-small cell lung cancer cell lines PC9
non-small cell lung cancer cell lines HCC827
non-small cell lung cancer cell lines H1975
Experiment
None
Institute
The Second Affiliated Hospital of Nanjing Medical University
Institute of Biochemistry and Cell Biology at the Chinese Academy of Sciences
Country
China
China
Continent
Asia
Asia