Circ_0006528

ncRNA information

ncRNA name

Circ_0006528

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-1299/CDK8

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Circ_0006528 Contributes to Paclitaxel Resistance of Breast Cancer Cells by Regulating miR-1299/CDK8 Axis

Tissue resource

breast cancer tissues and corresponding normal tissues

breast cancer cell lines MCF10A

breast cancer cell lines BT-549

breast cancer cell lines ZR-75-30

Experiment

None


Institute

Luoyang Central Hospital Affiliated to Zhengzhou University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian