Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircNRIP1
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-211-5p/HOXC8
Cancer name
Ovarian Cancer
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Downregulation of circNRIP1 Suppresses the Paclitaxel Resistance of Ovarian Cancer via Regulating the miR-211-5p/HOXC8 Axis
Tissue resource
paclitaxel-sensitive ovarian cancer tissues and paclitaxel-resistant ovarian cancer tissues and adjacent normal tissues
human ovarian epithelial cell lines HOEC
human ovarian cancer cell lines A2780
human ovarian cancer cell lines SKOV3
ovarian cancer paclitaxel-resistant cell lines A2780/paclitaxel
ovarian cancer paclitaxel-resistant cell lines SKOV3/paclitaxel
Experiment
None
Institute
Xingtai People's Hospital
China Center for Type Culture Collection
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.