Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
SNHG7
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-186
Cancer name
Breast Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Trastuzumab
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Down-regulation of SNHG7-targeted miR-186 can reverse trastuzumab resistance of BC cells
Tissue resource
breast cancer cell lines HER2+
breast cancer cell lines SK-BR-3
breast cancer cell lines AU565
Experiment
None
Institute
Country
Continent
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.