Circ_0000260

ncRNA information

ncRNA name

Circ_0000260

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-129-5p/MMP11

Cancer information

Cancer name

Gastric Adenocarcinoma

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

circ_0000260 knockdown attenuated CDDP resistance during tumor growth in vivo by regulating the expression of miR-129-5p and MMP11

Tissue resource

gastric adenocarcinoma tumor tissues and adjacent normal tissues

gastric adenocarcinoma cell lines HGC27

gastric adenocarcinoma cell lines AGS

Experiment

None


Institute

The Second People's Hospital of Yibin

EK-Bioscience

Country

China

China

Continent

Asia

Asia