Circ_0007841

ncRNA information

ncRNA name

Circ_0007841

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-129-5p/JAG1

Cancer information

Cancer name

Multiple Myeloma

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Bortezomib

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Depletion of circ_0007841 inhibits multiple myeloma development and BTZ resistance via miR-129-5p/JAG1 axis

Tissue resource

bone marrow from multiple myeloma patients and healthy individuals

human normal plasma cell lines nPCs

multiple myeloma cell lines OPM2

multiple myeloma cell lines JJN3

Experiment

None


Institute

The Fifth Affiliated Hospital of Zhengzhou University

Miltenyi Biotec

Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH

Country

China

Germany

Germany

Continent

Asia

European

European