AFAP1-AS1

ncRNA information

ncRNA name

AFAP1-AS1

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-195-5p/FKBP1A

Cancer information

Cancer name

Prostate Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

AFAP1-AS1 silencing attenuated the resistance of PTX-resistant PCa cells to PTX by downregulating FKBP1A via sponging miR-195-5p

Tissue resource

prostate cancer tissues and corresponding nearby healthy tissues

human normal prostate epithelial cell lines HprEC

prostate cancer cell lines PC3

prostate cancer cell lines DU145

Experiment

None


Institute

Yantaishan Hospital

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian