Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
Exosome LncRNA UCA1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
SOCS3/EZH2
Cancer name
Pancreatic Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Gemcitabine
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Exosomal lncRNA UCA1 Derived From Pancreatic Stellate Cells Promotes Gemcitabine Resistance in Pancreatic Cancer via the SOCS3/EZH2 Axis
Tissue resource
pancreatic cancer tissues and adjacent normal tissues
human pancreatic cancer cell lines PSC
human pancreatic cancer cell lines PANC-1
human embryonic kidney cell lines 293T
Experiment
None
Institute
Shengjing Hospital of China Medical University
Mingzhou Biological Technology Co Ltd
Wuhan Procell Life Science & Technology Co Ltd
Country
China
China
China
Continent
Asia
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.