hsa-miR-122-5p

ncRNA information

ncRNA name

hsa-miR-122-5p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

PKM2

Cancer information

Cancer name

Prostate Cancer

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Docetaxel

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MicroRNA-122 regulates docetaxel resistance of prostate cancer cells by regulating PKM2

Tissue resource

Prostate cancer docetaxel-resistant cell lines LNCaP/Docetaxel

Prostate cancer docetaxel-sensitive cell lines LNCaP

Experiment

None


Institute

the Cell Bank of Type Culture Collection of the Chinese Academy of Sciences

Country

China

Continent

Asia