Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa_circ_0030998
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-558
Cancer name
Lung Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Down
Number of patients
28
Male patients
18
Female patients
20(<=60)+26(>60)
Age range and number
Not available
PMID
Description
A novel circular RNA, hsa_circ_0030998 suppresses lung cancer tumorigenesis and Taxol resistance by sponging miR-558
Tissue resource
pairs of surgically excised lung cancer and adjacent tissues
human bronchial epithelial cell lines HBE
lung cancer cell lines A549
lung cancer cell lines H1299
lung cancer cell lines H358
lung cancer cell lines PC9
human embryonic kidney cell lines 293T
Experiment
46
Institute
Tianjin First Central Hospital
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.