CircMCTP2

ncRNA information

ncRNA name

CircMCTP2

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-99a-5p/MTMR3

Cancer information

Cancer name

Gastric Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

68

Male patients

32

Female patients

39(<60)+61(>=60)

Age range and number

Not available

Research information

PMID

Description

CircMCTP2 sensitizes GC to CDDP through the upregulation of MTMR3 by sponging miR-99a-5p

Tissue resource

gastric cancer tissues

gastric cancer cell lines BGC823

gastric cancer cell lines SGC7901

gastric cancer cell lines cisplatin-resistant SGC7901/CDDP

Experiment

100


Institute

the First Affiliated Hospital of Nanjing Medical University

the Cell Bank of Type Culture Collection of Chinese Academy of Sciences

Country

China

Continent

Asia