Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircMCTP2
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-99a-5p/MTMR3
Cancer name
Gastric Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
68
Male patients
32
Female patients
39(<60)+61(>=60)
Age range and number
Not available
PMID
Description
CircMCTP2 sensitizes GC to CDDP through the upregulation of MTMR3 by sponging miR-99a-5p
Tissue resource
gastric cancer tissues
gastric cancer cell lines BGC823
gastric cancer cell lines SGC7901
gastric cancer cell lines cisplatin-resistant SGC7901/CDDP
Experiment
100
Institute
the First Affiliated Hospital of Nanjing Medical University
the Cell Bank of Type Culture Collection of Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.