Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircRAB3IP
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-133a-3p/miR-133b/SGK1
Cancer name
Prostate Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Enzalutamide
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
The circRAB3IP Mediated by eIF4A3 and LEF1 Contributes to Enzalutamide Resistance in Prostate Cancer by Targeting miR-133a-3p/miR-133b/SGK1 Pathway
Tissue resource
prostate cell lines 22Rv1
prostate cancer tissues
prostate cell lines C4-2
prostate cell lines C4-2-EnzR
prostate cell lines LNCaP
prostate cell lines LNCaP-EnzR
Experiment
None
Institute
Shanghai Institutes for Biological Sciences
Beijing Chaoyang Hospital
University of Rochester Medical Center
Country
China
China
United States
Continent
Asia
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.