hsa-miR-610

ncRNA information

ncRNA name

hsa-miR-610

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

HDGF

Cancer information

Cancer name

Hepatocellular Carcinoma

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiRNA-610 acts as a tumour suppressor to depress the cisplatin resistance in hepatocellular carcinoma through targeted silencing of hepatoma-derived growth factor

Tissue resource

hepatocellular carcinoma and control normal liver tissues

human liver cell lines HL7702

human hepatocellular carcinoma cell lines HepG2

Experiment

None


Institute

Shengjing Hospital of China Medical University

China Academy of Chinese Medical Sciences

Country

China

China

Continent

Asia

Asia