hsa-miR-1260a

ncRNA information

ncRNA name

hsa-miR-1260a

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

SFRP1

Cancer information

Cancer name

Lung Adenocarcinoma

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Taxane

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

miR-1260b Activates Wnt Signaling by Targeting Secreted Frizzled-Related Protein 1 to Regulate Taxane Resistance in Lung Adenocarcinoma

Tissue resource

advanced lung adenocarcinoma tissues

human lung adenocarcinoma cell lines H1299

human lung adenocarcinoma cell lines A549

Experiment

None


Institute

the Affiliated Hospital of Jiangsu University

Shanghai Institute of Cell Biology

Country

China

China

Continent

Asia

Asia