ncRNA name
hsa-miR-1260a
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
SFRP1
Cancer name
Lung Adenocarcinoma
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Taxane
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
miR-1260b Activates Wnt Signaling by Targeting Secreted Frizzled-Related Protein 1 to Regulate Taxane Resistance in Lung Adenocarcinoma
Tissue resource
advanced lung adenocarcinoma tissues
human lung adenocarcinoma cell lines H1299
human lung adenocarcinoma cell lines A549
Experiment
None
Institute
the Affiliated Hospital of Jiangsu University
Shanghai Institute of Cell Biology
Country
China
China
Continent
Asia
Asia