Circ_0005198

ncRNA information

ncRNA name

Circ_0005198

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-198/TRIM14

Cancer information

Cancer name

Glioma

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Temozolomide

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis

Tissue resource

glioma samples and normal brain tissues

human glioma cell lines U87

human glioma cell lines U251

human glioma cell lines U138

human glioma cell lines LN18

normal human astrocytes cell lines NHA

Experiment

None


Institute

the Third Xiangya Hospital of Central South University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian