Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
Circ_0005198
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-198/TRIM14
Cancer name
Glioma
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Temozolomide
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis
Tissue resource
glioma samples and normal brain tissues
human glioma cell lines U87
human glioma cell lines U251
human glioma cell lines U138
human glioma cell lines LN18
normal human astrocytes cell lines NHA
Experiment
None
Institute
the Third Xiangya Hospital of Central South University
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.