hsa_circ_0000714

ncRNA information

ncRNA name

hsa_circ_0000714

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-370-3p/RAB17

Cancer information

Cancer name

Ovarian Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Knockdown of Circular RNA Hsa_circ_0000714 Can Regulate RAB17 by Sponging miR-370-3p to Reduce Paclitaxel Resistance of Ovarian Cancer Through CDK6/RB Pathway

Tissue resource

human epithelial ovarian cancer cell lines SKOV3

human epithelial ovarian cancer cell lines A2780

Experiment

None


Institute

Beijing Shijitan Hospital

Beijing Shijitan Hospital

Country

China

China

Continent

Asia

Asia