hsa-miR-218-5p

ncRNA information

ncRNA name

hsa-miR-218-5p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

LRRC28

Cancer information

Cancer name

Multiple Myeloma

Cancer site

None

Treatment information

Treatment type

Chemotherapy

Drug

Bortezomib

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

miR-218 is decreased in MM that contributes to BTZ resistance via targeting LRRC28, which might be used as a novel therapeutic target for multiple myeloma

Tissue resource

Experiment

None


Institute

Country

Continent