Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
LINC00312
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
DNA-PKcs
Cancer name
Nasopharyngeal Carcinoma
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Radiotherapy
Impact of wild-type ncRNA on radiotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma
Tissue resource
diagnosed NPC tissue biopsies and chronic inflammation of nasopharyngeal mucosa tissue biopsies
human immortalized normal nasopharyngeal epithelial cell lines NP69
nasopharyngeal carcinoma cell lines CNE1
nasopharyngeal carcinoma cell lines CNE2
nasopharyngeal carcinoma cell lines HNE1
nasopharyngeal carcinoma cell lines HONE1
Experiment
None
Institute
the Affiliated Cancer Hospital of Xiangya School of Medicine
the Advanced Research Center of Central South University
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.