LINC00312

ncRNA information

ncRNA name

LINC00312

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

DNA-PKcs

Cancer information

Cancer name

Nasopharyngeal Carcinoma

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

radiotherapy

Treatment name

Impact of wild-type ncRNA on resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma

Tissue resource

diagnosed NPC tissue biopsies and chronic inflammation of nasopharyngeal mucosa tissue biopsies

human immortalized normal nasopharyngeal epithelial cell lines NP69

nasopharyngeal carcinoma cell lines CNE1

nasopharyngeal carcinoma cell lines CNE2

nasopharyngeal carcinoma cell lines HNE1

nasopharyngeal carcinoma cell lines HONE1

Experiment

None


Institute

the Affiliated Cancer Hospital of Xiangya School of Medicine

the Advanced Research Center of Central South University

Country

China

China

Continent

Asia

Asia