Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
MCM3AP-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-138/FOXC1
Cancer name
Gastric Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MCM3AP-AS1 promotes cisplatin resistance in gastric cancer cells via the miR-138/FOXC1 axis
Tissue resource
gastric cancer cell lines AGS
gastric cancer cell lines MKN45
gastric cancer cell lines NCI-N87
gastric cancer cell lines SNU638
normal gastric mucosa epithelial cell lines GES-1
human embryonic kidney cell lines 293T
Experiment
None
Institute
the Cell Bank of Type Culture Collection of the Chinese Academy of Sciences
Country
Continent
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.