Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
MACC1-AS1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
NSD2
Cancer name
Esophageal Squamous Cell Carcinoma
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
30
Male patients
4
Female patients
13(<=60)+21(>60)
Age range and number
Not available
PMID
Description
Long non-coding RNAs MACC1-AS1 mediate NSD2-induced cisplatin resistance in esophageal squamous cell carcinoma
Tissue resource
tumor specimens and paired noncancerous tissues from patients with esophageal squamous cell carcinoma
esophageal squamous cell carcinoma cell lines KYSE150
esophageal squamous cell carcinoma cell lines KYSE30
esophageal squamous cell carcinoma cell lines EC109
Experiment
34
Institute
Shanghai Institutes for Biological Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.