KCNQ1OT1

ncRNA information

ncRNA name

KCNQ1OT1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-454/USP47

Cancer information

Cancer name

Nasopharyngeal Carcinoma

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Long non-coding RNA KCNQ1OT1 promotes nasopharyngeal carcinoma cell cisplatin resistance via the miR-454/USP47 axis

Tissue resource

nasopharyngeal carcinoma cell lines 5-8F

nasopharyngeal carcinoma cell lines SUNE-1

specimens from npc patients

Experiment

None


Institute

the Cell Bank of Type Culture Collection of the Chinese Academy of Sciences

the Cell Bank of Type Culture Collection of the Chinese Academy of Sciences

Zhuji Central Hospital 

Country

China

Continent

Asia