Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircFOXM1
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-1324/MECP2
Cancer name
Hepatocellular Carcinoma
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Sorafenib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
circFOXM1 contributes to sorafenib resistance of hepatocellular carcinoma cells by regulating MECP2 via miR-1324
Tissue resource
pairs of fresh hepatocellular carcinomatissues and ANTs
hepatocellular carcinoma cell lines HepG2
hepatocellular carcinoma cell lines Huh-7
normal human liver cell lines LO2
Experiment
None
Institute
the Department of Hepato-Biliary Surgery, Dongguan People's Hospital, Southern Medical University
the Chinese Academy of Sciences Cell Bank Type Culture Collection
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.