Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
TRPM2-AS
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-138-5p/SDC3
Cancer name
Ovarian Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
23(<=60)+19(>60)
Age range and number
Not available
PMID
Description
LncRNA TRPM2-AS promotes ovarian cancer progression and cisplatin resistance by sponging miR-138-5p to release SDC3 mRNA
Tissue resource
ovarian cancer tissues and contralateral normal fallopian tube tissues
human ovarian surface epithelial cell lines IOSE-80
ovarian cancer cell lines EB0405
ovarian cancer cell lines CAOV3
ovarian cancer cell lines HEY
ovarian cancer cell lines SKOV3
Experiment
42
Institute
Tongji Hospital
the National Infrastructure of Cell Line Resource
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.