TRPM2-AS

ncRNA information

ncRNA name

TRPM2-AS

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-138-5p/SDC3

Cancer information

Cancer name

Ovarian Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

23(<=60)+19(>60)

Age range and number

Not available

Research information

PMID

Description

LncRNA TRPM2-AS promotes ovarian cancer progression and cisplatin resistance by sponging miR-138-5p to release SDC3 mRNA

Tissue resource

ovarian cancer tissues and contralateral normal fallopian tube tissues

human ovarian surface epithelial cell lines IOSE-80

ovarian cancer cell lines EB0405

ovarian cancer cell lines CAOV3

ovarian cancer cell lines HEY

ovarian cancer cell lines SKOV3

Experiment

42


Institute

Tongji Hospital

the National Infrastructure of Cell Line Resource

Country

China

Continent

Asia