Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
DANCR
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-874-3P/ATG16L1
Cancer name
Acute Myeloid Leukemia
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Cytarabine
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Long noncoding RNA DANCR confers cytarabine resistance in acute myeloid leukemia by activating autophagy via the miR-874-3P/ATG16L1 axis
Tissue resource
human acute myeloid leukemia cell lines HL60
human acute myeloid leukemia cell lines U937
human acute myeloid leukemia cell lines KG1a
Experiment
None
Institute
American Type Culture Collection
Country
United States
Continent
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.