DANCR

ncRNA information

ncRNA name

DANCR

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-874-3P/ATG16L1

Cancer information

Cancer name

Acute Myeloid Leukemia

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cytarabine

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Long noncoding RNA DANCR confers cytarabine resistance in acute myeloid leukemia by activating autophagy via the miR-874-3P/ATG16L1 axis

Tissue resource

human acute myeloid leukemia cell lines HL60

human acute myeloid leukemia cell lines U937

human acute myeloid leukemia cell lines KG1a

Experiment

None


Institute

American Type Culture Collection

Country

United States

Continent

North Amercian