Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircCSPP1
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-944/FZD7
Cancer name
Colorectal Cancer
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Doxorubicin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Circular RNA circCSPP1 knockdown attenuates doxorubicin resistance and suppresses tumor progression of colorectal cancer via miR-944/FZD7 axis
Tissue resource
colorectal cancer doxorubicin sensitive or resistant tissues
colorectal cancer cell lines LoVo
colorectal cancer cell lines HCT116
Experiment
None
Institute
Zhengzhou Anorectal Hospital
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.