Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
OIP5-AS1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-27b-3p/TRIM14
Cancer name
Oral Squamous Cell Carcinoma
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Long non-coding RNA OIP5-AS1 contributes to cisplatin resistance of oral squamous cell carcinoma through the miR-27b-3p/TRIM14 axis
Tissue resource
Samples of OSCC tumor tissues and normal adjacent tissues
normal human oral keratinocyte cell lines NHOK
human ovarian squamous cell carcinoma cell lines SCC-15
human ovarian squamous cell carcinoma cell lines SCC-9
human ovarian squamous cell carcinoma cell lines Cal-27
human ovarian squamous cell carcinoma cell lines HSC-3
Experiment
None
Institute
the First Hospital of Qiqihar
the Cell Bank of Type Culture Collection of the Chinese Academy of Sciences
American Type Culture Collection
Cell Bank of Japanese Collection of Research Bioresources
Country
China
China
United States
Japan
Continent
Asia
Asia
North Amercian
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.