CircARVCF

ncRNA information

ncRNA name

CircARVCF

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-1205/FGFR1

Cancer information

Cancer name

Gastric Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

20

Male patients

17

Female patients

25-71

Age range and number

Not available

Research information

PMID

Description

CircARVCF Contributes to Cisplatin Resistance in Gastric Cancer by Altering miR-1205 and FGFR1

Tissue resource

gastric cancer and matched adjacent non-tumor tissues

human normal gastric mucosa cell lines GES-1

gastric cancer cell lines N87

gastric cancer cell lines HGC-27

gastric cancer cell lines MKN-45

gastric cancer cell lines AGS

Experiment

37


Institute

Huai'an First People's hospital

Procell

Country

China

China

Continent

Asia

Asia