Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
LINCROR
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
TWIST1
Cancer name
Hepatocellular Carcinoma
Cancer site
None
Treatment type
Chemotherapy
Drug
Doxorubicin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
The present study provided evidence that lincāROR promoted HCC resistance to DOX by inducing EMT via interacting with TWIST1
Tissue resource
hepatocellular carcinoma cell lines Hep3B
hepatocellular carcinoma cell lines Huh7
hepatocellular carcinoma cell lines SNU387
hepatocellular carcinoma cell lines SNU449
Experiment
None
Institute
American Type Culture Collection
Country
United States
Continent
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.