hsa-miR-125a-5p

ncRNA information

ncRNA name

hsa-miR-125a-5p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

LIMK1

Cancer information

Cancer name

Cervical Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MicroRNA-125a-5p targets LIMK1 to inhibit cisplatin resistance of cervical cancer cells

Tissue resource

cervical cancer tumor tissues and corresponding adjacent tissues

human cervical cancer cell lines C-33A

human cervical cancer cell lines CaSKi

human cervical epithelial cell lines HUCEC

Experiment

None


Institute

the Department of Pathology of Shengli Oilfield Central Hospital

the China Infrastructure of Cell Line Resources, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences

Country

China

China

Continent

Asia

Asia