Circ_0071589

ncRNA information

ncRNA name

Circ_0071589

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

MiR-526b-3p/KLF12

Cancer information

Cancer name

Colorectal Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

29

Male patients

27

Female patients

31(<60)+25(>=60)

Age range and number

Not available

Research information

PMID

Description

Downregulation of Circ_0071589 Suppresses Cisplatin Resistance in Colorectal Cancer by Regulating the MiR-526b-3p/KLF12 Axis

Tissue resource

colorectal cancer tissue samples

colorectal cancer cell lines HCT116

colorectal cancer cell lines LOVO

normal human colorectal mucosa cell lines FHC

Experiment

56


Institute

Hainan General Hospital 

Bena Culture Collection

Country

China

China

Continent

Asia

Asia