Lnc-PICSAR

ncRNA information

ncRNA name

Lnc-PICSAR

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-485-5p/REV3L

Cancer information

Cancer name

Cutaneous Squamous-Cell Carcinoma

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Lnc-PICSAR contributes to cisplatin resistance by miR-485-5p/REV3L axis in cutaneous squamous cell carcinoma

Tissue resource

serum samples were obtained from cutaneous squamous cell carcinoma patients and healthy volunteers

normal epidermal keratinocytes cell lines NHEKs

cutaneous squamous cell carcinoma cell lines A431

Experiment

None


Institute

the Affiliated Hospital of Jiangnan University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian