Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
UCA1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
HK2/LDHA
Cancer name
Colorectal Cancer
Cancer site
None
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
UCA1 could directly regulate glycolysis by regulating HK2 and LDHA expression, which contributes to Taxol resistance
Tissue resource
Experiment
None
Institute
Country
Continent
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.