Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
SNHG26
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
PGK1/Akt/mTOR
Cancer name
Tongue Squamous Cell Carcinoma
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
These findings suggest that lncRNA-SNHG26 may be a promising target for inhibiting TSCC progression and improving sensitivity to cisplatin chemotherapy in TSCC
Tissue resource
human tongue squamous cell carcinoma cell lines CAL27
human tongue squamous cell carcinoma cell lines SCC15
human tongue squamous cell carcinoma cisplatin-resistant cell lines CAL27/CDDP
Experiment
None
Institute
Shaanxi Provincial Key Laboratory of Craniomaxillofacial Precision Medicine
Shaanxi Provincial Key Laboratory of Craniomaxillofacial Precision Medicine
Sun Yat-sen Memorial Hospital
Country
China
China
China
Continent
Asia
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.