OSER1-AS1

ncRNA information

ncRNA name

OSER1-AS1

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-612/FOXM1

Cancer information

Cancer name

Lung Adenocarcinoma

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Gefitinib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA OSER1-AS1 interacts with miR-612/FOXM1 axis to modulate gefitinib resistance of lung adenocarcinoma

Tissue resource

lung adenocarcinoma cell lines A549

lung adenocarcinoma cell lines H1299

lung adenocarcinoma cell lines SPCA1

normal bronchial epithelial cells 16HBE

Experiment

None


Institute

American Type Culture Collection

Country

United States

Continent

North Amercian