ncRNA name
OSER1-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-612/FOXM1
Cancer name
Lung Adenocarcinoma
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Gefitinib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
LncRNA OSER1-AS1 interacts with miR-612/FOXM1 axis to modulate gefitinib resistance of lung adenocarcinoma
Tissue resource
lung adenocarcinoma cell lines A549
lung adenocarcinoma cell lines H1299
lung adenocarcinoma cell lines SPCA1
normal bronchial epithelial cells 16HBE
Experiment
None
Institute
American Type Culture Collection
Country
United States
Continent
North Amercian