FENDRR

ncRNA information

ncRNA name

FENDRR

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

FOXC2

Cancer information

Cancer name

Gastric Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Adriamycin/Vincristine

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

FENDRR/FOXC2 Axis Contributes to Multidrug Resistance in Gastric Cancer and Correlates With Poor Prognosis

Tissue resource

gastric cancer tissue microarray containing cases and paired adjacent non-cancerous tissues

gastric cancer multidrug-resistant cell lines SGC7901/adriamycin

gastric cancer multidrug-resistant cell lines SGC7901/vincristine

gastric cancer cell linesSGC7901

Experiment

None


Institute

the Academy of Military Medical Science

Country

China

Continent

Asia