HOXA11-AS

ncRNA information

ncRNA name

HOXA11-AS

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

microRNA-98/PBX3

Cancer information

Cancer name

Nasopharyngeal Carcinoma

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

HOXA11-AS induces cisplatin resistance by modulating the microRNA-98/PBX3 axis in nasopharyngeal carcinoma

Tissue resource

nasopharyngeal carcinoma tissues and adjacent normal tissues

human normal nasopharyngeal epithelial cell lines NP-69

human nasopharyngeal carcinoma cell lines 5–8F

human nasopharyngeal carcinoma cell lines SUNE1

Experiment

None


Institute

the Shanghai Ninth People's Hospital

BeNa Culture Collection

Country

China

China

Continent

Asia

Asia