UCA1

ncRNA information

ncRNA name

UCA1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-613

Cancer information

Cancer name

Leukemia

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Daunorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA UCA1 elevates the resistance of human leukemia cells to daunorubicin by the PI3K/AKT pathway via sponging miR-613

Tissue resource

human bone marrow stromal cell lines HS-5

acute leukemia cell lines HL-60

acute leukemia cell lines U-937

Experiment

None


Institute

American Type Culture Collection

Country

United States

Continent

North Amercian