Exosome CircXIAP

ncRNA information

ncRNA name

Exosome CircXIAP

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-1182/TPD52

Cancer information

Cancer name

Prostate Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Docetaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Exosomal Circ-XIAP Promotes Docetaxel Resistance in Prostate Cancer by Regulating miR-1182/TPD52 Axis

Tissue resource

prostate cancer tumor tissues from sensitive and resistant tissues

prostate cancer cell lines 22Rv1

prostate cancer cell lines VCaP

prostate cancer cell lines DU145

prostate cancer cell lines PC3

human normal prostate epithelial cell lines RWPE-1

Experiment

None


Institute

The Central Hospital of Zhumadian

COBIOER

Country

China

China

Continent

Asia

Asia