ncRNA name
Exosome CircXIAP
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-1182/TPD52
Cancer name
Prostate Cancer
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Docetaxel
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Exosomal Circ-XIAP Promotes Docetaxel Resistance in Prostate Cancer by Regulating miR-1182/TPD52 Axis
Tissue resource
prostate cancer tumor tissues from sensitive and resistant tissues
prostate cancer cell lines 22Rv1
prostate cancer cell lines VCaP
prostate cancer cell lines DU145
prostate cancer cell lines PC3
human normal prostate epithelial cell lines RWPE-1
Experiment
None
Institute
The Central Hospital of Zhumadian
COBIOER
Country
China
China
Continent
Asia
Asia