Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircPVT1
Specific or universal ncRNAs
Universal ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-137/TRIAP1
Cancer name
Osteosarcoma
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Doxorubicin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Circular RNA circPVT1 Contributes to Doxorubicin Resistance of Osteosarcoma Cells by Regulating TRIAP1 via miR-137
Tissue resource
normal bone tissue samples and osteosarcoma tissue samples
human fetal osteoblastic cell lines hFOB1.19
human osteosarcoma cell lines KHOS
human osteosarcoma cell lines U2OS
human embryonic kidney cell lines 293T
Experiment
None
Institute
The First Hospital of Jilin University
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.