CircHIPK2

ncRNA information

ncRNA name

CircHIPK2

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-338-3p/CHTOP

Cancer information

Cancer name

Ovarian Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

18(<=50)+28(>50)

Age range and number

Not available

Research information

PMID

Description

Silencing circHIPK2 might suppress DDP-resistant OvCa through regulating miR-338-3p/CHTOP axis

Tissue resource

ovarian cancer tissues and adjacent healthy tissues

human ovarian surface epithelium cell lines IOSE80

ovarian serous cystadenocarcinoma cell lines SKOV3

ovarian endometrioid adenocarcinoma cell lines A2780

Experiment

46


Institute

Cancer Hospital of China Medical University

the BeNa Culture Collection

Country

China

China

Continent

Asia

Asia