hsa-miR-214-5p

ncRNA information

ncRNA name

hsa-miR-214-5p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

HCG11

Downstream target

SOX4

Cancer information

Cancer name

Colorectal Carcinoma

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

HLA complex group 11 is involved in colorectal carcinoma cisplatin resistance via the miR-214-5p/SOX4 axis

Tissue resource

pairs of colorectal cancer and non-cancerous tissues

primary colorectal cancer cell lines HCT116

primary colorectal cancer cell lines SW620

primary colorectal cancer cell lines SW480

primary colorectal cancer cell lines HT-29

normal colon tissue cell lines HIEC-6

Experiment

None


Institute

the First Affiliated Hospital of Yangtze University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian