CircPRDM2

ncRNA information

ncRNA name

CircPRDM2

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-760/EZH2

Cancer information

Cancer name

Osteosarcoma

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

CircPRDM2 Contributes to Doxorubicin Resistance of Osteosarcoma by Elevating EZH2 via Sponging miR-760

Tissue resource

osteosarcoma tissue specimens and adjacent nontumor tissue

osteosarcoma cell lines KHOS

osteosarcoma cell lines MG63

osteoblast cell lines hFOB1.19

Experiment

None


Institute

Tianjin Union Medical Center

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian